USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: DC1L2_HUMAN USC-OGP 2-DE database:  DC1L2_HUMAN DC1L2_HUMAN General information about the entry View entry in simple text format Entry name DC1L2_HUMAN Primary accession number O43237 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Cytoplasmic dynein 1 light intermediate chain 2; AltName: Full=Dynein light intermediate chain 2, cytosolic; Short=LIC-2; AltName: Full=LIC53/55;. Gene name Name=DYNC1LI2 Synonyms=DNCLI2, LIC2 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1157: pI=6.47; Mw=52149 Cross-references UniProtKB/Swiss-Prot O43237; DC1L2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name DC1L2_HUMAN Primary accession number O43237 Secondary accession number(s) A8K6V1 B4DZP4 Q8TAT3 Sequence was last modified on  June 1, 1998 (version 1) Annotations were last modified on  March 15, 2017 (version 139) Name and origin of the protein Description RecName: Full=Cytoplasmic dynein 1 light intermediate chain 2; AltName: Full=Dynein light intermediate chain 2, cytosolic; Short=LIC-2; AltName: Full=LIC53/55; Gene name Name=DYNC1LI2 Synonyms=DNCLI2, LIC2 Encoded on Name=DYNC1LI2; Synonyms=DNCLI2, LIC2 Keywords Alternative splicing; ATP-binding; Complete proteome; Cytoplasm; Cytoskeleton; Dynein; Methylation; Microtubule; Motor protein; Nucleotide-binding; Phosphoprotein; Reference proteome; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL AF035812; AAB88513.1; -; mRNA EMBL AK291766; BAF84455.1; -; mRNA EMBL AK303031; BAG64156.1; -; mRNA EMBL AC018557; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL AC044802; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471092; EAW83039.1; -; Genomic_DNA EMBL BC025959; AAH25959.1; -; mRNA CCDS CCDS10818.1; -. [O43237-1]; . CCDS CCDS67049.1; -. [O43237-2]; . RefSeq NP_001273086.1; NM_001286157.1. [O43237-2]; . RefSeq NP_006132.1; NM_006141.2. [O43237-1]; . UniGene Hs.369068; -; . ProteinModelPortal O43237; -; . SMR O43237; -; . BioGrid 108120; 39; . IntAct O43237; 19; . MINT MINT-2999261; -; . STRING 9606.ENSP00000258198; -; . iPTMnet O43237; -; . PhosphoSitePlus O43237; -; . BioMuta DYNC1LI2; -; . EPD O43237; -; . MaxQB O43237; -; . PaxDb O43237; -; . PeptideAtlas O43237; -; . PRIDE O43237; -; . DNASU 1783; -; . Ensembl ENST00000258198; ENSP00000258198; ENSG00000135720. [O43237-1]; . Ensembl ENST00000443351; ENSP00000394289; ENSG00000135720. [O43237-2]; . GeneID 1783; -; . KEGG hsa:1783; -; . UCSC uc002eqb.2; human. [O43237-1]; . CTD 1783; -; . DisGeNET 1783; -; . GeneCards DYNC1LI2; -; . HGNC HGNC:2966; DYNC1LI2; . HPA HPA057201; -; . MIM 611406; gene; . neXtProt NX_O43237; -; . OpenTargets ENSG00000135720; -; . PharmGKB PA27438; -; . eggNOG KOG3905; Eukaryota; . eggNOG ENOG410XQS4; LUCA; . GeneTree ENSGT00390000008295; -; . HOGENOM HOG000236263; -; . HOVERGEN HBG005546; -; . InParanoid O43237; -; . KO K10416; -; . OMA KKPDPNM; -; . OrthoDB EOG091G0B3J; -; . PhylomeDB O43237; -; . TreeFam TF352602; -; . Reactome R-HSA-2132295; MHC class II antigen presentation; . Reactome R-HSA-6807878; COPI-mediated anterograde transport; . Reactome R-HSA-6811436; COPI-independent Golgi-to-ER retrograde traffic; . ChiTaRS DYNC1LI2; human; . GeneWiki DYNC1LI2; -; . GenomeRNAi 1783; -; . PRO PR:O43237; -; . Proteomes UP000005640; Chromosome 16; . Bgee ENSG00000135720; -; . CleanEx HS_DYNC1LI2; -; . ExpressionAtlas O43237; baseline and differential; . Genevisible O43237; HS; . GO GO:0005813; C:centrosome; IDA:UniProtKB; . GO GO:0005868; C:cytoplasmic dynein complex; IBA:GO_Central; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005874; C:microtubule; IEA:UniProtKB-KW; . GO GO:0005524; F:ATP binding; IEA:UniProtKB-KW; . GO GO:0045504; F:dynein heavy chain binding; IBA:GO_Central; . GO GO:0003777; F:microtubule motor activity; IEA:InterPro; . GO GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome; . GO GO:0051642; P:centrosome localization; IEA:Ensembl; . GO GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:Reactome; . GO GO:0000226; P:microtubule cytoskeleton organization; IBA:GO_Central; . GO GO:0007018; P:microtubule-based movement; IBA:GO_Central; . Gene3D 3.40.50.300; -; 2; . InterPro IPR008467; Dynein1_light_intermed_chain; . InterPro IPR022780; Dynein_light_int_chain; . InterPro IPR027417; P-loop_NTPase; . PANTHER PTHR12688; PTHR12688; 1; . Pfam PF05783; DLIC; 1; . SUPFAM SSF52540; SSF52540; 2; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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